Stem Cell Nano-mesh Regenerates Tendons

A polymer mesh fabric seeded with stem cells can help in the regeneration of rotator cuff tendons.

Stem Cell Fabric Innovation Regrows Rotator Cuffs – [uconn.edu]

The combination of the “nano-mesh” with stem cells seems to be critical. Surgeons will sometimes inject stem cells into rotator cuff repairs, but results from this technique are mixed. Stem cells alone don’t necessarily stick around at the surgery site. Adding the mesh changes that. The mesh, made of a nanostructured polymer combining polycaprolactone and polyphosphazene – pioneered in Laurencin’s laboratory – provides an attractive habitat for the stem cells to hunker down. Once they settle into the rotator cuff location, the stem cells begin sending out signals directing other cells to align and grow into tendon tissue.

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