Soccer Molecule of Youth? Fullerene C60 Increases Lifespan by +90% and Protects Against Free Radicals – [suppversity.blogspot.com]
Put some “soccer balls” in your olive oil and live into your late 150s
Since study was designed as a general investigation – not as a test for the longevity effects of the “soccer fullerene” – the actual study consisted of a couple of experiments designed to…
- test the preparation technique – 50mg of C60 dissolved in 10ml of virgine olive oil
- pharmacokinetic and biodistribution studies – after oral and intra-peritoneal administration
- chronic toxicity effects – 0.8mg C60 every day for the 1st week, then weekly until the end of the 2nd month, then every two weeks until the end of the 7th month
- anti-oxidant effects – 0.8mg C60 pre-treatment for 7 days before administration of a single dose of CCl4 (1ml/kg bw) as an oxidative stressor
…where the result that the staggered administration of an olive oil + C60 mixture to eighteen 10-months old rats could increase their lifespan by up to 90% was more or less an incidental side-finding of the experiment that had been designed to elucidate the chronic toxicity effects (see above).
Fullerene C60 administration doubles rat lifespan with no toxicity – [kurzweilai.net]
Researchers at the University of Paris and colleagues fed the molecule fullerene (C60 or “buckyballs”) dissolved in olive oil to rats and found it almost doubles their lifespan, with no chronic toxicity.
The results suggest that the effect of C60, an antioxidant, on lifespan is mainly due to the attenuation of age-associated increases in oxidative stress, according to the researchers.