1953 – DNA – Watson and Crick

In 1953, James Watson and Francis Crick published an article in the journal, “Nature”. The article, titled “Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid”, described the DNA double helix structure which stores and replicates genetic information. When the two identical halves of the helix separate, the chemical bonds which held them together act as a template to build replacements, forming two new double helix pairs. This allows cells to divide but replicate the genetic information that controls their behavior.

PRECURSOR:

1866 – Mendel on inherited traits
1869 – Miescher describes DNA as nuclein
1906 – Delbruck (born)
1909 – Morgan – genes in chromosomes
1919 – Levene – polynucleotide structure
1943 – Avery connects genetic information with DNA
1944 – Schrodinger wrote “What is Life?”
1948 – Pauling – alpha helix
1950 – Chargaff’s rules
1952 – Franklin – x-ray image of DNA

CONCURRENT
1953 – Pauling proposes triple helix

SUBSEQUENT:
1977 – DNA is sequenced
1995 – genome of a bacteria
2003 – Human Genome project completed

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